Infections in Oncology GRANULOCYTE TRANSFUSIONS: TIME FOR A SECOND LOOK
نویسندگان
چکیده
The patient who is profoundly neutropenic and expected to remain so for an extended period of time is at high risk for a serious bacterial or fungal infection.[1,2] In approximately one third of episodes of fever and neutropenia (absolute neutrophil count <500 cells/mm>6), a diagnosis is documented, and of these, a small proportion is life threatening.[2,3] Successful therapy for documented infections is predicated on recovery from neutropenia and the efficacy of available antimicrobial agents. The morbidity and mortality are higher in patients with neutropenia that persists for more than a few days and results in progressive infection, as defined by lack of response to antimicrobial therapy.[2,4]
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